Natriuretic Peptide Receptor C (NPR3) (NM_000908) Human Recombinant Protein
Product Specifications
Background
This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Overview
Recombinant protein of human natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (NPR3)
Synonyms
ANP-C; ANPR-C; ANPRC; C5orf23; GUCY2B; NPR-C; NPRC
Gene ID
4883
UniProt
P17342, Q60I31
Accession Number mRNA
NM_000908
Chromosomal Location
5p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
59.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NPR3
Species
Human
Protein ID
NP_000899
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4883
Uniprot URL
https://www.uniprot.org/uniprot/P17342
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000908
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000899
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