ADH6 (NM_001102470) Human Recombinant Protein
Product Specifications
Background
This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
ADH-5
Gene ID
130
UniProt
P28332, Q8IUN7
Accession Number mRNA
NM_001102470
Chromosomal Location
4q23
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism
Field of Research
Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
39.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ADH6
Species
Human
Protein ID
NP_001095940
Overview
Recombinant protein of human alcohol dehydrogenase 6 (class V) (ADH6), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/130
Uniprot URL
https://www.uniprot.org/uniprot/P28332
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001102470
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001095940
Curated Selection
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