SCARA5 (NM_173833) Human Recombinant Protein
Product Specifications
Background
Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1) .[UniProtKB/Swiss-Prot Function]
Synonyms
NET33; Tesr
Gene ID
286133
UniProt
Q6ZMJ2
Accession Number mRNA
NM_173833
Chromosomal Location
8p21.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
53.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SCARA5
Species
Human
Protein ID
NP_776194
Overview
Recombinant protein of human scavenger receptor class A, member 5 (putative) (SCARA5)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/286133
Uniprot URL
https://www.uniprot.org/uniprot/Q6ZMJ2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_173833
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_776194
Curated Selection
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