NUDT2 (NM_147173) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified. [provided by RefSeq, Sep 2011]
Synonyms
APAH1
Gene ID
318
UniProt
P50583
Accession Number mRNA
NM_147173
Chromosomal Location
9p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Purine metabolism, Pyrimidine metabolism
Field of Research
Purine metabolism, Pyrimidine metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
16.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NUDT2
Species
Human
Protein ID
NP_671702
Overview
Recombinant protein of human nudix (nucleoside diphosphate linked moiety X) -type motif 2 (NUDT2), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/318
Uniprot URL
https://www.uniprot.org/uniprot/P50583
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_147173
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_671702
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
