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NUDT2 (NM_147173) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified. [provided by RefSeq, Sep 2011]

Overview

Recombinant protein of human nudix (nucleoside diphosphate linked moiety X) -type motif 2 (NUDT2), transcript variant 3

Synonyms

APAH1

Gene ID

318

UniProt

P50583

Accession Number mRNA

NM_147173

Chromosomal Location

9p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Purine metabolism, Pyrimidine metabolism

Field of Research

Purine metabolism, Pyrimidine metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

16.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NUDT2

Species

Human

Protein ID

NP_671702

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/318

Uniprot URL

https://www.uniprot.org/uniprot/P50583

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_147173

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_671702

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