CYLD (NM_015247) Human Recombinant Protein
Product Specifications
Background
This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Synonyms
BRSS; CDMT; CYLD1; CYLDI; EAC; FTDALS8; MFT; MFT1; SBS; TEM; USPL2
Gene ID
1540
UniProt
Q9NQC7
Accession Number mRNA
NM_015247
Chromosomal Location
16q12.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
RIG-I-like receptor signaling pathway
Field of Research
RIG-I-like receptor signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
107.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CYLD
Species
Human
Protein ID
NP_056062
Overview
Recombinant protein of human cylindromatosis (turban tumor syndrome) (CYLD), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1540
Uniprot URL
https://www.uniprot.org/uniprot/Q9NQC7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015247
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056062
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