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PDLIM2 (NM_176871) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Synonyms

MYSTIQUE; SLIM

Gene ID

64236

UniProt

Q96JY6

Accession Number mRNA

NM_176871

Chromosomal Location

8p21.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

39 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PDLIM2

Species

Human

Protein ID

NP_789847

Overview

Purified recombinant protein of Homo sapiens PDZ and LIM domain 2 (mystique) (PDLIM2), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/64236

Uniprot URL

https://www.uniprot.org/uniprot/Q96JY6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_176871

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_789847

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