PDLIM2 (NM_176871) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Overview
Purified recombinant protein of Homo sapiens PDZ and LIM domain 2 (mystique) (PDLIM2), transcript variant 1
Synonyms
MYSTIQUE; SLIM
Gene ID
64236
UniProt
Q96JY6
Accession Number mRNA
NM_176871
Chromosomal Location
8p21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
39 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PDLIM2
Species
Human
Protein ID
NP_789847
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/64236
Uniprot URL
https://www.uniprot.org/uniprot/Q96JY6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_176871
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_789847
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