GnRH (GNRH1) (NM_001083111) Human Recombinant Protein
Product Specifications
Background
This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015]
Overview
Recombinant protein of human gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) (GNRH1), transcript variant 2
Synonyms
GNRH; GRH; LHRH; LNRH
Gene ID
2796
UniProt
P01148
Accession Number mRNA
NM_001083111
Chromosomal Location
8p21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
GnRH signaling pathway
Field of Research
GnRH signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
7.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GNRH1
Species
Human
Protein ID
NP_001076580
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2796
Uniprot URL
https://www.uniprot.org/uniprot/P01148
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001083111
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001076580
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