GPR73A (PROKR1) (NM_138964) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016]
Synonyms
GPR73; GPR73a; PK-R1; PKR1; ZAQ
Gene ID
10887
UniProt
Q8TCW9
Accession Number mRNA
NM_138964
Chromosomal Location
2p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, GPCR, Transmembrane
Molecular Weight
44.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PROKR1
Species
Human
Protein ID
NP_620414
Overview
Recombinant protein of human prokineticin receptor 1 (PROKR1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10887
Uniprot URL
https://www.uniprot.org/uniprot/Q8TCW9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_138964
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_620414
Curated Selection
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