LASP1 (NM_006148) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012]
Overview
Recombinant protein of human LIM and SH3 protein 1 (LASP1)
Synonyms
Lasp-1; MLN50
Gene ID
3927
UniProt
Q14847, A0A024R1S8
Accession Number mRNA
NM_006148
Chromosomal Location
17q12
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
29.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LASP1
Species
Human
Protein ID
NP_006139
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3927
Uniprot URL
https://www.uniprot.org/uniprot/Q14847
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006148
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006139
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