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SYCE1 (NM_130784) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

Overview

Purified recombinant protein of Homo sapiens synaptonemal complex central element protein 1 (SYCE1), transcript variant 1

Synonyms

C10orf94; CT76; POF12; SPGF15

Gene ID

93426

UniProt

Q8N0S2

Accession Number mRNA

NM_130784

Chromosomal Location

10q26.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

32.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SYCE1

Species

Human

Protein ID

NP_570140

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/93426

Uniprot URL

https://www.uniprot.org/uniprot/Q8N0S2

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_130784

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_570140

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