CHRDL2 (NM_015424) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration. [provided by RefSeq, Jan 2015]
Synonyms
BNF1; CHL2
Gene ID
25884
UniProt
Q6WN34
Accession Number mRNA
NM_015424
Chromosomal Location
11q13.4
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
28009989
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
49.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CHRDL2
Species
Human
Protein ID
NP_056239
Overview
Recombinant protein of human chordin-like 2 (CHRDL2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25884
Uniprot URL
https://www.uniprot.org/uniprot/Q6WN34
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015424
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056239
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