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CHRDL2 (NM_015424) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration. [provided by RefSeq, Jan 2015]

Overview

Recombinant protein of human chordin-like 2 (CHRDL2)

Synonyms

BNF1; CHL2

Gene ID

25884

UniProt

Q6WN34

Accession Number mRNA

NM_015424

Chromosomal Location

11q13.4

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Activity

28009989

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

49.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CHRDL2

Species

Human

Protein ID

NP_056239

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/25884

Uniprot URL

https://www.uniprot.org/uniprot/Q6WN34

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_015424

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_056239

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