ERF1 (ETF1) (NM_004730) Human Recombinant Protein
Product Specifications
Background
This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD) . Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]
Synonyms
D5S1995; ERF; ERF1; RF1; SUP45L1; TB3-1
Gene ID
2107
UniProt
P62495
Accession Number mRNA
NM_004730
Chromosomal Location
5q31.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
48.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ETF1
Species
Human
Protein ID
NP_004721
Overview
Recombinant protein of human eukaryotic translation termination factor 1 (ETF1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2107
Uniprot URL
https://www.uniprot.org/uniprot/P62495
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004730
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004721
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