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Transglutaminase 3 (TGM3) (NM_003245) Human Recombinant Protein

Product Specifications

Background

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM3)

Synonyms

TGE; UHS2

Gene ID

7053

UniProt

Q08188

Accession Number mRNA

NM_003245

Chromosomal Location

20p13

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

76.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TGM3

Species

Human

Protein ID

NP_003236

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7053

Uniprot URL

https://www.uniprot.org/uniprot/Q08188

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003245

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003236

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