Transglutaminase 3 (TGM3) (NM_003245) Human Recombinant Protein
Product Specifications
Background
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. [provided by RefSeq, Jul 2008]
Synonyms
TGE; UHS2
Gene ID
7053
UniProt
Q08188
Accession Number mRNA
NM_003245
Chromosomal Location
20p13
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
76.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TGM3
Species
Human
Protein ID
NP_003236
Overview
Recombinant protein of human transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7053
Uniprot URL
https://www.uniprot.org/uniprot/Q08188
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003245
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003236
Curated Selection
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