ARHGAP22 (NM_021226) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Overview
Purified recombinant protein of Homo sapiens Rho GTPase activating protein 22 (ARHGAP22)
Synonyms
RhoGAP2; RhoGap22
Gene ID
58504
UniProt
Q7Z5H3
Accession Number mRNA
NM_021226
Chromosomal Location
10q11.22-q11.23
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
76.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ARHGAP22
Species
Human
Protein ID
NP_067049
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/58504
Uniprot URL
https://www.uniprot.org/uniprot/Q7Z5H3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021226
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_067049
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