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RIPPLY2 (NM_001009994) Human Recombinant Protein

Product Specifications

Background

This gene encodes a nuclear protein that belongs to a novel family of proteins required for vertebrate somitogenesis. Members of this family have a tetrapeptide WRPW motif that is required for interaction with the transcriptional repressor Groucho and a carboxy-terminal Ripply homology domain/Bowline-DSCR-Ledgerline conserved region required for transcriptional repression. Null mutant mice die soon after birth and display defects in axial skeleton segmentation due to defective somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Synonyms

C6orf159; dJ237I15.1; SCDO6

Gene ID

134701

UniProt

Q5TAB7

Accession Number mRNA

NM_001009994

Chromosomal Location

6q14.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

13.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RIPPLY2

Species

Human

Protein ID

NP_001009994

Overview

Recombinant protein of human ripply2 homolog (zebrafish) (RIPPLY2)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/134701

Uniprot URL

https://www.uniprot.org/uniprot/Q5TAB7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001009994

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001009994

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