IL17E (IL25) (NM_172314) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Synonyms
IL17E
Gene ID
64806
UniProt
Q9H293
Accession Number mRNA
NM_172314
Chromosomal Location
14q11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein, Transmembrane
Molecular Weight
16.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IL25
Species
Human
Protein ID
NP_758525
Overview
Purified recombinant protein of Homo sapiens interleukin 25 (IL25), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/64806
Uniprot URL
https://www.uniprot.org/uniprot/Q9H293
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_172314
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_758525
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