ADAMTS6 (NM_197941) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. [provided by RefSeq, Mar 2016]
Overview
Recombinant protein of human ADAM metallopeptidase with thrombospondin type 1 motif, 6 (ADAMTS6)
Synonyms
ADAM-TS 6; ADAM-TS6; ADAMTS-6
Gene ID
11174
UniProt
Q9UKP5, Q5IR90
Accession Number mRNA
NM_197941
Chromosomal Location
5q12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Protease
Molecular Weight
122.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ADAMTS6
Species
Human
Protein ID
NP_922932
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11174
Uniprot URL
https://www.uniprot.org/uniprot/Q9UKP5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_197941
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_922932
Frequently Asked Questions
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