Alkyl DHAP synthase (AGPS) (NM_003659) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human alkylglycerone phosphate synthase (AGPS)

Synonyms

ADAP-S; ADAS; ADHAPS; ADPS; ALDHPSY; RCDP3

Gene ID

8540

UniProt

O00116

Accession Number mRNA

NM_003659

Chromosomal Location

2q31.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Ether lipid metabolism, Metabolic pathways

Field of Research

Ether lipid metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

67 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.