Alkyl DHAP synthase (AGPS) (NM_003659) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]
Synonyms
ADAP-S; ADAS; ADHAPS; ADPS; ALDHPSY; RCDP3
Gene ID
8540
UniProt
O00116
Accession Number mRNA
NM_003659
Chromosomal Location
2q31.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Ether lipid metabolism, Metabolic pathways
Field of Research
Ether lipid metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
67 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
AGPS
Species
Human
Protein ID
NP_003650
Overview
Recombinant protein of human alkylglycerone phosphate synthase (AGPS)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8540
Uniprot URL
https://www.uniprot.org/uniprot/O00116
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003659
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003650
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