Nogo A (RTN4) (NM_007008) Human Recombinant Protein
Product Specifications
Background
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Synonyms
ASY; Nbla00271; Nbla10545; NI220/250; NOGO; NOGO-A; Nogo-B; Nogo-C; NOGOC; NSP; NSP-CL; RTN-X; RTN4-A
Gene ID
57142
UniProt
Q9NQC3
Accession Number mRNA
NM_007008
Chromosomal Location
2p16.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
22.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RTN4
Species
Human
Protein ID
NP_008939
Overview
Recombinant protein of human reticulon 4 (RTN4), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57142
Uniprot URL
https://www.uniprot.org/uniprot/Q9NQC3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007008
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_008939
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
