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OTOA (NM_144672) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is specifically expressed in the inner ear, and is located at the interface between the apical surface of the inner ear sensory epithelia and their overlying acellular gels. It is prposed that this protein is involved in the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22 (DFNB22) . Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Overview

Recombinant protein of human otoancorin (OTOA), transcript variant 1

Synonyms

CT108; DFNB22

Gene ID

146183

UniProt

Q05BM7

Accession Number mRNA

NM_144672

Chromosomal Location

16p12.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

126.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

OTOA

Species

Human

Protein ID

NP_653273

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/146183

Uniprot URL

https://www.uniprot.org/uniprot/Q05BM7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_144672

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_653273

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