PQBP1 (NM_001032384) Human Recombinant Protein

Product Specifications

Background

This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked cognitive disability. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.[provided by RefSeq, Nov 2009]

Overview

Purified recombinant protein of Homo sapiens polyglutamine binding protein 1 (PQBP1), transcript variant 5

Synonyms

MRX2; MRX55; MRXS3; MRXS8; NPW38; RENS1; SHS

Gene ID

10084

UniProt

O60828, A0A0S2Z4V5

Accession Number mRNA

NM_001032384

Chromosomal Location

Xp11.23

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Spliceosome

Field of Research

Spliceosome

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

30.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.