TNFAIP3 (NM_006290) Human Recombinant Protein

Product Specifications

Background

This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF) . The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]

Overview

Recombinant protein of human tumor necrosis factor, alpha-induced protein 3 (TNFAIP3)

Synonyms

A20; AISBL; OTUD7C; TNFA1P2

Gene ID

7128

UniProt

P21580

Accession Number mRNA

NM_006290

Chromosomal Location

6q23.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

NOD-like receptor signaling pathway

Field of Research

NOD-like receptor signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

89.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.