VMAT2 (SLC18A2) (NM_003054) Human Recombinant Protein

Product Specifications

Background

This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments. [provided by RefSeq, Jun 2018]

Overview

Recombinant protein of human solute carrier family 18 (vesicular monoamine), member 2 (SLC18A2)

Synonyms

PKDYS2; SVAT; SVMT; VAT2; VMAT2

Gene ID

6571

UniProt

Q05940

Accession Number mRNA

NM_003054

Chromosomal Location

10q25.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Parkinson's disease

Field of Research

Parkinson's disease

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

55.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.