VMAT2 (SLC18A2) (NM_003054) Human Recombinant Protein
Product Specifications
Background
This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments. [provided by RefSeq, Jun 2018]
Overview
Recombinant protein of human solute carrier family 18 (vesicular monoamine), member 2 (SLC18A2)
Synonyms
PKDYS2; SVAT; SVMT; VAT2; VMAT2
Gene ID
6571
UniProt
Q05940
Accession Number mRNA
NM_003054
Chromosomal Location
10q25.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Parkinson's disease
Field of Research
Parkinson's disease
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
55.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SLC18A2
Species
Human
Protein ID
NP_003045
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6571
Uniprot URL
https://www.uniprot.org/uniprot/Q05940
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003054
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003045
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