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CD21 (CR2) (NM_001877) Human Recombinant Protein

Product Specifications

Background

This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) . Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Synonyms

C3DR; CD21; CR; CVID7; SLEB9

Gene ID

1380

UniProt

P20023

Accession Number mRNA

NM_001877

Chromosomal Location

1q32.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

B cell receptor signaling pathway, Complement and coagulation cascades, Hematopoietic cell lineage

Field of Research

B cell receptor signaling pathway, Complement and coagulation cascades, Hematopoietic cell lineage

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

111.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CR2

Species

Human

Protein ID

NP_001868

Overview

Recombinant protein of human complement component (3d/Epstein Barr virus) receptor 2 (CR2), transcript variant 2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1380

Uniprot URL

https://www.uniprot.org/uniprot/P20023

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001877

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001868

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