C15ORF27 (TMEM266) (NM_152335) Human Recombinant Protein

Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum (PubMed:25165868, PubMed:30810529) . Despite the presence of a voltage-sensor segment, does not form a functional ion channel and its precise role remains unclear (PubMed:25165868, PubMed:30810529) . Undergoes both rapid and slow structural rearrangements in response to changes in voltage (PubMed:30810529) . Contains a zinc-binding site that can regulate the slow conformational transition (PubMed:30810529) .[UniProtKB/Swiss-Prot Function]

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.