TIGIT (NM_173799) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH) . The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]
Synonyms
VSIG9; VSTM3; WUCAM
Gene ID
201633
UniProt
Q495A1
Accession Number mRNA
NM_173799
Chromosomal Location
3q13.31
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
26.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TIGIT
Species
Human
Protein ID
NP_776160
Overview
Recombinant protein of human T cell immunoreceptor with Ig and ITIM domains (TIGIT)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/201633
Uniprot URL
https://www.uniprot.org/uniprot/Q495A1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_173799
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_776160
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