Protein Kinase D2 (PRKD2) (NM_001079881) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms
HSPC187; nPKC-D2; PKD2
Gene ID
25865
UniProt
Q9BZL6
Accession Number mRNA
NM_001079881
Chromosomal Location
19q13.32
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
96.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PRKD2
Species
Human
Protein ID
NP_001073350
Overview
Recombinant protein of human protein kinase D2 (PRKD2), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25865
Uniprot URL
https://www.uniprot.org/uniprot/Q9BZL6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001079881
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001073350
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