BAT3 (BAG6) (NM_004639) Human Recombinant Protein
Product Specifications
Background
This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
BAG-6; BAT3; D6S52E; G3
Gene ID
7917
UniProt
P46379
Accession Number mRNA
NM_004639
Chromosomal Location
6p21.33
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Stem cell - Pluripotency
Molecular Weight
119.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BAG6
Species
Human
Protein ID
NP_004630
Overview
Recombinant protein of human HLA-B associated transcript 3 (BAT3), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7917
Uniprot URL
https://www.uniprot.org/uniprot/P46379
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004639
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004630
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