PAOX (NM_207127) Human Recombinant Protein

Flavoenzyme which catalyzes the oxidation of N (1) -acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380) . Can also oxidize N (1) -acetylspermidine to putrescine. Substrate specificity: N (1) -acetylspermine = N (1) -acetylspermidine > N (1), N (12) -diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380) .[UniProtKB/Swiss-Prot Function]

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.