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CRAT (NM_004003) Human Recombinant Protein

Product Specifications

Background

This gene encodes carnitine O-acetyltransferase, a member of the carnitine acyltransferase family and a key metabolic pathway enzyme which plays an important role in energy homeostasis and fat metabolism. This enzyme catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acyl-CoA/CoA. It is found in both the mitochondria and the peroxisome. Alternative splicing results in transcript variants encoding different isoforms that may localize to different subcellular compartments. [provided by RefSeq, Oct 2016]

Synonyms

CAT; CAT1; NBIA8

Gene ID

1384

UniProt

P43155

Accession Number mRNA

NM_004003

Chromosomal Location

9q34.11

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

68.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CRAT

Species

Human

Protein ID

NP_003994

Overview

Recombinant protein of human carnitine acetyltransferase (CRAT), transcript variant 2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1384

Uniprot URL

https://www.uniprot.org/uniprot/P43155

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004003

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003994

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