OSCAR (NM_130771) Human Recombinant Protein
Product Specifications
Background
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
Synonyms
PIgR-3; PIGR3
Gene ID
126014
UniProt
Q8IYS5, A0A087X1R2
Accession Number mRNA
NM_130771
Chromosomal Location
19q13.42
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
29 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
OSCAR
Species
Human
Protein ID
NP_570127
Overview
Purified recombinant protein of Homo sapiens osteoclast associated, immunoglobulin-like receptor (OSCAR), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/126014
Uniprot URL
https://www.uniprot.org/uniprot/Q8IYS5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_130771
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_570127
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