DRP1 (DNM1L) (NM_012062) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF) . Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Synonyms
DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; OPA5
Gene ID
10059
UniProt
O00429, B4DYR6
Accession Number mRNA
NM_012062
Chromosomal Location
12p11.21
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis, Fc gamma R-mediated phagocytosis
Field of Research
Endocytosis, Fc gamma R-mediated phagocytosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
25853493
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
81.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DNM1L
Species
Human
Protein ID
NP_036192
Overview
Recombinant protein of human dynamin 1-like (DNM1L), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10059
Uniprot URL
https://www.uniprot.org/uniprot/O00429
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012062
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036192
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6102804-01 1 mg
1-[4-(2-Aminoethylphenyl)sulfonyl]-3-(trans-4-hydroxycyclohexyl)urea Trifluoroacetate
Ask
View Details MBS6102804-02 5x 1 mg
1-[4-(2-Aminoethylphenyl)sulfonyl]-3-(trans-4-hydroxycyclohexyl)urea Trifluoroacetate
Ask
View Details