RAP1B (NM_001010942) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011]
Overview
Recombinant protein of human RAP1B, member of RAS oncogene family (RAP1B), transcript variant 2
Synonyms
K-REV; RAL1B
Gene ID
5908
UniProt
P61224, A0A024RB87
Accession Number mRNA
NM_001010942
Chromosomal Location
12q15
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Long-term potentiation, MAPK signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma
Field of Research
Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Long-term potentiation, MAPK signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
20.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RAP1B
Species
Human
Protein ID
NP_001010942
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5908
Uniprot URL
https://www.uniprot.org/uniprot/P61224
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001010942
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001010942
Frequently Asked Questions
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