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RAP1B (NM_001010942) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011]

Overview

Recombinant protein of human RAP1B, member of RAS oncogene family (RAP1B), transcript variant 2

Synonyms

K-REV; RAL1B

Gene ID

5908

UniProt

P61224, A0A024RB87

Accession Number mRNA

NM_001010942

Chromosomal Location

12q15

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Long-term potentiation, MAPK signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

Field of Research

Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Long-term potentiation, MAPK signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

20.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RAP1B

Species

Human

Protein ID

NP_001010942

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5908

Uniprot URL

https://www.uniprot.org/uniprot/P61224

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001010942

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001010942

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