CK1 epsilon (CSNK1E) (NM_001894) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]

Overview

Recombinant protein of human casein kinase 1, epsilon (CSNK1E), transcript variant 2

Synonyms

CKIe; CKIepsilon; HCKIE

Gene ID

1454

UniProt

P49674, Q5U045

Accession Number mRNA

NM_001894

Chromosomal Location

22q13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Circadian rhythm - mammal, Hedgehog signaling pathway, Wnt signaling pathway

Field of Research

Circadian rhythm - mammal, Hedgehog signaling pathway, Wnt signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase

Molecular Weight

47.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.