INPP5A (NM_005539) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins (1,4,5) P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human inositol polyphosphate-5-phosphatase, 40kDa (INPP5A)

Synonyms

5PTASE

Gene ID

3632

UniProt

Q14642

Accession Number mRNA

NM_005539

Chromosomal Location

10q26.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system

Field of Research

Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

47.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

INPP5A

Species

Human

Protein ID

NP_005530

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3632

Uniprot URL

https://www.uniprot.org/uniprot/Q14642

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005539

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005530

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