LCE3A (NM_178431) Human Recombinant Protein
Product Specifications
Background
A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable) . Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens (PubMed:28634035) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human late cornified envelope 3A (LCE3A)
Synonyms
LEP13
Gene ID
353142
UniProt
Q5TA76
Accession Number mRNA
NM_178431
Chromosomal Location
1q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LCE3A
Species
Human
Protein ID
NP_848518
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/353142
Uniprot URL
https://www.uniprot.org/uniprot/Q5TA76
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_178431
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_848518
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