CKII alpha (CSNK2A1) (NM_001895) Human Recombinant Protein

Product Specifications

Background

Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. Multiple transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Apr 2018]

Overview

Recombinant protein of human casein kinase 2, alpha 1 polypeptide (CSNK2A1), transcript variant 2

Synonyms

CK2A1; Cka1; Cka2; CKII; CSNK2A3; OCNDS

Gene ID

1457

UniProt

P68400

Accession Number mRNA

NM_001895

Chromosomal Location

20p13

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Adherens junction, Tight junction, Wnt signaling pathway

Field of Research

Adherens junction, Tight junction, Wnt signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase

Molecular Weight

45 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.