HTRA1 (NM_002775) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human HtrA serine peptidase 1 (HTRA1)
Synonyms
ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11
Gene ID
5654
UniProt
Q92743
Accession Number mRNA
NM_002775
Chromosomal Location
10q26.13
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
2926904229572155
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease, Secreted Protein
Molecular Weight
49 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HTRA1
Species
Human
Protein ID
NP_002766
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5654
Uniprot URL
https://www.uniprot.org/uniprot/Q92743
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002775
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002766
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