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MTMR7 (NM_004686) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Mar 2009]

Synonyms

DKFZp781E194; MGC163449; MGC163451

Gene ID

9108

UniProt

Q9Y216, B7ZAG8, B7Z9Q7

Accession Number mRNA

NM_004686

Chromosomal Location

8p22

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism

Field of Research

Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Phosphatase

Molecular Weight

75.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MTMR7

Species

Human

Protein ID

NP_004677

Overview

Recombinant protein of human myotubularin related protein 7 (MTMR7)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9108

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y216

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004686

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004677

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