AIP1 (MAGI2) (NM_012301) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human membrane associated guanylate kinase, WW and PDZ domain containing 2 (MAGI2)

Synonyms

ACVRIP1; AIP-1; AIP1; ARIP1; MAGI-2; NPHS15; SSCAM

Gene ID

9863

UniProt

Q86UL8

Accession Number mRNA

NM_012301

Chromosomal Location

7q21.11

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Tight junction

Field of Research

Tight junction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

158.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.