AIP1 (MAGI2) (NM_012301) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]
Synonyms
ACVRIP1; AIP-1; AIP1; ARIP1; MAGI-2; NPHS15; SSCAM
Gene ID
9863
UniProt
Q86UL8
Accession Number mRNA
NM_012301
Chromosomal Location
7q21.11
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Tight junction
Field of Research
Tight junction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
158.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MAGI2
Species
Human
Protein ID
NP_036433
Overview
Recombinant protein of human membrane associated guanylate kinase, WW and PDZ domain containing 2 (MAGI2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9863
Uniprot URL
https://www.uniprot.org/uniprot/Q86UL8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012301
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036433
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