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Synphilin 1 (SNCAIP) (NM_005460) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Overview

Recombinant protein of human synuclein, alpha interacting protein (SNCAIP)

Synonyms

Sph1; SYPH1

Gene ID

9627

UniProt

Q9Y6H5

Accession Number mRNA

NM_005460

Chromosomal Location

5q23.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Parkinson's disease

Field of Research

Parkinson's disease

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

100.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SNCAIP

Species

Human

Protein ID

NP_005451

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9627

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y6H5

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005460

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005451

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