GIP (NM_004123) Human Recombinant Protein
Selected Variant
PH34207M5
Size: 20 µg
Product Specifications
Background
This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human gastric inhibitory polypeptide (GIP)
Synonyms
Gastric inhibitory polypeptide; glucose-dependent insulinotropic polypeptide
Gene ID
2695
UniProt
P09681
Accession Number mRNA
NM_004123
Chromosomal Location
17q21.32
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
4.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GIP
Species
Human
Protein ID
NP_004114
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2695
Uniprot URL
https://www.uniprot.org/uniprot/P09681
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004123
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004114
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