CHTF8 (NM_001039690) Human Recombinant Protein
Product Specifications
Background
This gene encodes a short protein that forms part of the Ctf18 replication factor C (RFC) complex that occurs in both yeast and mammals. The heteroheptameric RFC complex plays a role in sister chromatid cohesion and may load the replication clamp PCNA (proliferating cell nuclear antigen) onto DNA during DNA replication and repair. This gene is ubiquitously expressed and has been shown to have reduced expression in renal and prostate tumors. Alternatively spliced transcript variants have been described. This gene has a pseudogene on chromosome X. [provided by RefSeq, Oct 2018]
Synonyms
CTF8; DERPC
Gene ID
54921
UniProt
P0CG13
Accession Number mRNA
NM_001039690
Chromosomal Location
16q22.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
13.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CHTF8
Species
Human
Protein ID
NP_001034779
Overview
Recombinant protein of human CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) (CHTF8), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54921
Uniprot URL
https://www.uniprot.org/uniprot/P0CG13
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001039690
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001034779
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