ANKHD1 (NM_024668) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Sep 2010]
Synonyms
MASK; MASK1; PP2500; VBARP
Gene ID
54882
UniProt
Q8IWZ3
Accession Number mRNA
NM_024668
Chromosomal Location
5q31.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
64.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ANKHD1
Species
Human
Protein ID
NP_078944
Overview
Recombinant protein of human ankyrin repeat and KH domain containing 1 (ANKHD1), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54882
Uniprot URL
https://www.uniprot.org/uniprot/Q8IWZ3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024668
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_078944
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