Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

AKR1D1 (NM_005989) Human Recombinant Protein

Selected Variant

PH34076M5

Size: 20 µg

Product Specifications

Background

The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta (4) -3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010]

Overview

Recombinant protein of human aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (AKR1D1)

Synonyms

3o5bred; CBAS2; SRD5B1

Gene ID

6718

UniProt

P51857

Accession Number mRNA

NM_005989

Chromosomal Location

7q33

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Androgen and estrogen metabolism, C21-Steroid hormone metabolism, Metabolic pathways, Primary bile acid biosynthesis

Field of Research

Androgen and estrogen metabolism, C21-Steroid hormone metabolism, Metabolic pathways, Primary bile acid biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

37.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

AKR1D1

Species

Human

Protein ID

NP_005980

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6718

Uniprot URL

https://www.uniprot.org/uniprot/P51857

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005989

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005980

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog