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FUT8 (NM_178155) Human Recombinant Protein

Product Specifications

Background

This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]

Overview

Recombinant protein of human fucosyltransferase 8 (alpha (1, 6) fucosyltransferase) (FUT8), transcript variant 1

Synonyms

CDGF; CDGF1

Gene ID

2530

UniProt

Q9BYC5, Q546E0, A8K8P8

Accession Number mRNA

NM_178155

Chromosomal Location

14q23.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Keratan sulfate biosynthesis, Metabolic pathways, N-Glycan biosynthesis

Field of Research

Keratan sulfate biosynthesis, Metabolic pathways, N-Glycan biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

66.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FUT8

Species

Human

Protein ID

NP_835368

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2530

Uniprot URL

https://www.uniprot.org/uniprot/Q9BYC5

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_178155

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_835368

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