Pirin (PIR) (NM_003662) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the cupin superfamily. The encoded protein is an Fe (II) -containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
Synonyms
OTTHUMP00000022961; OTTHUMP00000022962; pirin; pirin (iron-binding nuclear protein)
Gene ID
8544
UniProt
O00625, A0A024RBX6
Accession Number mRNA
NM_003662
Chromosomal Location
Xp22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
31.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PIR
Species
Human
Protein ID
NP_003653
Overview
Recombinant protein of human pirin (iron-binding nuclear protein) (PIR), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8544
Uniprot URL
https://www.uniprot.org/uniprot/O00625
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003662
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003653
Curated Selection
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