Uroplakin II (UPK2) (NM_006760) Human Recombinant Protein
Product Specifications
Background
This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009]
Synonyms
UP2; UPII
Gene ID
7379
UniProt
O00526
Accession Number mRNA
NM_006760
Chromosomal Location
11q23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
16.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UPK2
Species
Human
Protein ID
NP_006751
Overview
Recombinant protein of human uroplakin 2 (UPK2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7379
Uniprot URL
https://www.uniprot.org/uniprot/O00526
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006760
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006751
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